Tetrahedron p. 4857 - 4868 (1997)
Update date:2022-09-26
Topics: Oxidation Regioselectivity Crystallization Yield NMR spectroscopy HPLC Stereochemistry Reduction Recrystallization Total synthesis Mass spectrometry (MS) Deprotection TLC (thin-layer chromatography) Protecting group Retrosynthetic analysis Coupling Reaction Chiral Auxiliary Reaction Optimization
Tanner, David
Tedenborg, Lars
Almario, Antonio
Pettersson, Ingrid
Csoeregh, Ingeborg
Kelly, Nicholas M.
Andersson, Pher G.
Hoegberg, Thomas
A convergent enantioselective total synthesis of the natural product (-)-balanol (1) is described. In addition to benzophenone fragment 8, key intermediates are chiral bicyclic aziridine 3 and the corresponding epoxide 4, both of which undergo highly regi
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Doi:10.1016/S0040-4039(00)60105-3
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