Total synthesis of balanol, part 2. Completion of the synthesis and investigation of the structure and reactivity of two key heterocyclic intermediates

Article abstract of DOI:10.1016/S0040-4020(97)00167-1

A convergent enantioselective total synthesis of the natural product (-)-balanol (1) is described. In addition to benzophenone fragment 8, key intermediates are chiral bicyclic aziridine 3 and the corresponding epoxide 4, both of which undergo highly regi