Carbohydrate Research p. 283 - 288 (1997)
Update date:2022-08-02
Topics:
Nishiyama, Yasufumi
Nishimura, Natsu
Kuroyanagi, Naoko
Maeba, Isamu
The synthesis of 3-β-D-ribofuranosyl-1 H-pyrazole-4-carboxamide (11) is described. Treatment of enaminone glycoside 1 with trimethyl orthoformate afforded the aldehyde 2. The aldehyde 2 was oximated with hydroxylamine. Oxime 3 was cyclized with hydrazine to afford the pyrazole 8. The pyrazole 8 was dehydrated with acetic anhydride, and the nitrile 9 was treated with nickel acetate in acetic acid. The resulting carboxamide 10 was deblocked by aq ammonia gave 11.
View MoreContact:+86-838-5655598
Address:Guanghan Nanfeng Industrial Zone
Jiaxing Carry Bio-Chem Technology Co.,Ltd
website:http://www.carrybiotech.com
Contact:0573-82788958
Address:Add.Fl 3th, Pharm Vally,Kaichuang Rd, Xiuzhou District, Jiaxing, Zhejiang,314031,China
Wuhan Sunrise Pharmaceutical Technology Co., Ltd
Contact:+86-27-83314682
Address:Room 340, New material Industrial base No.17, Gu Tian Five Lu , Qiaokou District, Wuhan , China
Zibo Ocean International Trade Co.,Ltd(expird)
Contact:+86 533 5160706
Address:1117, Hongtai Bld., Songling rd, Zichuan,Zibo,Shandong,China
Yixing Bluwat Chemicals Co., Ltd.
Contact:+86 510 87821568
Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
Doi:10.1021/ma302576p
(2013)Doi:10.1016/S0957-4166(97)00157-2
(1997)Doi:10.1021/ja01499a054
(1960)Doi:10.1016/j.bmcl.2011.05.108
(2011)Doi:10.1016/j.saa.2006.06.031
(2007)Doi:10.1002/anie.199710951
(1997)
