Cyclic homopentapeptides 3. Synthetic modifications to the capreomycins and tuberactinomycins: Compounds with activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci

DOI: 10.1016/S0960-894X(97)00188-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1149 - 1152 (1997)

Update date:2022-08-03

Topics:

Authors:

Linde II

Birsner Birsner

Chandrasekaran

Clancy Clancy

Howe Howe

Lyssikatos

MacLelland

Magee Magee

Petitpas

Rainville

Whipple Whipple

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00188-1

Modification and replacement of the β-lysine side chain of capreomycin and tuberactinomycin cyclic pentapeptide derivatives resulted in compounds with good antibacterial potency against multidrug-resistant pathogens.

Full text of DOI:10.1016/S0960-894X(97)00188-1

Products guided by the article

Product name:1-[(3S,9S,12S,15S)-6-[1-Benzyloxyamino-meth-(Z)-ylidene]-9,12-bis-hydroxymethyl-3-((R)-2-imino-hexahydro-pyrimidin-4-yl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaaza-cyclohexadec-15-yl]-3-(4-cyclohexyl-phenyl)-urea

Cas No:191722-64-2

R&D Labs maybe for 191722-64-2

JIANGSU GRAND XINYI PHARMACEUTICAL CO.,LTD

website:http://www.xypharm.com/

Contact:+86-515-84383317

Address:Chenli Road,Costal Chemical Area Binhai,Yancheng, Jiangsu,China
Zhushan County Tianxin Pharmaceutical & Chemical Co., Ltd.

Contact:0086-719-4224892

Address:Tutang Road, Chengguan Town, Zhushan County, Hubei Province
WENZHOU M&C FOREIGN TRADE CO.,LTD.

Contact:+86-577-88862917

Address:No.8 Liming West Road,Wenzhou,zhejiang,China
Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,
Fujian Wanke Pharmaceutical Co., LTD.

Contact:+86-598-5026002

Address:Economic development zone,jiangle county

Relevant to this article

Highly stereoselective additions of cuprates to a polyfunctional enone

Doi:10.1016/S0957-4166(97)00148-1
(1997)
Aminoborohydrides. 6. Diastereoselective Reduction of the Carbon-Nitrogen Double Bond in Chiral Imines Using Lithium Diethylaminoborohydride and Lithium Diisopropylaminoborohydride.

Doi:10.1016/S0040-4039(00)73507-6
(1994)
Synthesis and Structure of Seven-Coordinate Bismuth(v) Complexes with Benzenoid and Non-Benzenoid Arcne Ligands: Tri(aryl)tropolonatobismuth(v) Complexes

Doi:10.1002/anie.199600671
(1996)
Exploitation of Conformational Dynamics in Imparting Selective Inhibition for Related Matrix Metalloproteinases

Doi:10.1021/acsmedchemlett.7b00130
(2017)
Doi:10.1016/S0040-4039(01)87737-6
(1969)
Activation of a coordinated alkyne by electron transfer: Crystal structures of [Pd{PPh₂CH=C(Bu^t)NN=C(Bu^t)CH ₂PPh₂}{C(CO₂Me)=CH(CO₂Me)}] and [Pd{(Z,Z)PPh₂CH₂

Doi:10.1016/S0022-328X(99)00730-5
(2000)

Article Doi