Cyclic homopentapeptides 3. Synthetic modifications to the capreomycins and tuberactinomycins: Compounds with activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci

DOI: 10.1016/S0960-894X(97)00188-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1149 - 1152 (1997)

Update date:2022-08-03

Topics:

Authors:

Linde II

Birsner Birsner

Chandrasekaran

Clancy Clancy

Howe Howe

Lyssikatos

MacLelland

Magee Magee

Petitpas

Rainville

Whipple Whipple

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Article abstract of DOI:10.1016/S0960-894X(97)00188-1

Modification and replacement of the β-lysine side chain of capreomycin and tuberactinomycin cyclic pentapeptide derivatives resulted in compounds with good antibacterial potency against multidrug-resistant pathogens.

Full text of DOI:10.1016/S0960-894X(97)00188-1

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