Bioorganic and Medicinal Chemistry Letters p. 3081 - 3086 (1998)
Update date:2022-07-31
Topics:
Kuo, Michelle S.
Bock, Mark G.
Freidinger, Roger M.
Guidotti, Maribeth T.
Lis, Edward V.
Pawluczyk, Joseph M.
Perlow, Debra S.
Pettibone, Douglas J.
Quigley, Amy G.
Reiss, Duane R.
Williams, Peter D.
Woyden, Carla J.
Structure-activity studies on the oxytocin antagonist 1 (L-371,257) have identified a new series of high affinity, receptor-selective OT antagonists in which the N-acetyl-4-piperidinyl ether terminus in 1 has been replaced with a 1-(aryl)ethoxy group.
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