Bioorganic and Medicinal Chemistry Letters p. 71 - 74 (1998)
Update date:2022-08-03
Topics:
Auberson, Yves P.
Acklin, Pierre
Allgeier, Hans
Biollaz, Michel
Bischoff, Serge
Ofner, Silvio
Veenstra, Siem J.
Potent antagonists at the glycine-binding site of NMDA receptors, as well as dual antagonists acting also at AMPA receptors have been identified in a series of 5-arylaminomethylquinoxaline-2,3-diones. A study of the structure-activity relationship of these compounds is reported here.
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