Stereoselective synthesis of the C-linked analogue of β-D-galactopyranosyl-L-serine

Article abstract of DOI:10.1016/S0040-4020(98)83019-6

The coupling of the D-serinal derivative 7 with the D-galactopyranosylmethylene phosphorane generated from the phosphonium salt 6 and reduction of the resulting alkene led to the C-glycosylated amino alcohol 9 that in turn was oxidized to the title amino acid in 44% overall yield.