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68647-73-4

Basic Information
CAS No.: 68647-73-4
Name: Tea tree oil
Molecular Structure:
Molecular Structure of 68647-73-4 (Tea tree oil)
Formula: Null
Molecular Weight: 0
Synonyms: Oils, tea-tree;Oil ofMelaleuca alternifolia (cheel);
EINECS:
Density: 0.878 g/mL at 25 °C(lit.)
Melting Point:
Boiling Point: 165 °C(lit.)
Flash Point: 147 °F
Solubility:
Appearance: colourless to pale yellow liquid
Hazard Symbols: HarmfulXn, IrritantXi
Risk Codes: 22-36/37/38
Safety: 26-36
Transport Information:
PSA: 0.00000
LogP: 0.00000
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Chemistry

Product Name: Tea tree oil 
CAS NO: 68647-73-4
Density: 0.878 g/mL at 25 °C
Flash Point: 147 °F
Index of Refraction: n20/D 1.478
Boiling Point: 165 °C
Product Categories of Tea tree oil (CAS NO.68647-73-4): Flavors & Fragrances; Natural Plant Extract 

History

The indigenous Bundjalung people of eastern Australia use “tea trees” as a traditional medicine by inhaling the oils from the crushed leaves to treat coughs and colds. In addition, tea tree leaves are soaked to make an infusion to treat sore throats or skin ailments.
As opposed to the unextracted plant material, use of the oil itself did not become common practice until researcher Arthur Penfold published the first reports of its antimicrobial activity in a series of papers in the 1920s and 1930s. 
After the medicinal properties of the oil were first reported by Penfold in the 1920s,the commercial tea tree oil industry was born.
Interest in the oil was rekindled in the 1970s as part of the general renaissance of interest in natural products. in the 1970s and 1980s,Commercial plantations were established, which lead to mechanization and large-scale production of a consistent essential oil product.

Uses

 Tea tree oil (CAS NO.68647-73-4) once was used as a potent antiseptic in Australia anecdotally for much longer than there has been scientific evidence.
Recent studies support: Tea tree oil acts the role in skin care and treatment of various ailments.

Production

 Tea tree oil is taken from the leaves of the Melaleuca alternifolia which is native to the northeast coast of New South Wales, Australia.

Toxicity Data With Reference

child TDLo oral 500uL/kg (0.5mL/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

BEHAVIORAL: ATAXIA
Journal of Toxicology, Clinical Toxicology. Vol. 32, Pg. 461, 1994.
child TDLo oral 500uL/kg (0.5mL/kg) BEHAVIORAL: SLEEP

BEHAVIORAL: ATAXIA
Veterinary and Human Toxicology. Vol. 37, Pg. 557, 1995.
man TDLo oral 21uL/kg (0.021mL/kg) BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE"

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Medical Journal of Australia. Vol. 159, Pg. 830, 1993.
rabbit LDLo skin 5gm/kg (5000mg/kg)   Food and Chemical Toxicology. Vol. 26, Pg. 407, 1988.
rat LD50 oral 1900mg/kg (1900mg/kg)   Food and Chemical Toxicology. Vol. 26, Pg. 407, 1988.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Hazard Codes of Tea tree oil (CAS NO.68647-73-4): HarmfulXn, IrritantXi
Risk Statements: 22-36/37/38 
R22:Harmful if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: RJ3697600
Moderately toxic by ingestion. Low toxicity by skin contact. When heated to decomposition it emits acrid smoke and irritating vapors.

Specification

 Tea tree oil (CAS NO.68647-73-4) is also named as Oils, tea tree ; CCRIS 9084 ; Melaleuca alternifolia oil ; Oils, tea-tree ; T36-C7 ; Tea extract ; Tea leaf, absolute ; Tea oil ; Tea tree oil (Melaleuca alternifolia) .