Tetrahedron Letters p. 3237 - 3240 (1998)
Update date:2022-07-29
Topics:
Marco, J. Alberto
Carda, Miguel
Murga, Juan
Portoles, Raul
Falomir, Eva
Lex, Johann
The reaction of the 3,4-O-isopropylidene-L-(S)-erythrulose with hydroxylamine, followed by treatment of the resulting mixture of (E)- and (Z)-oximes with acetone and an acid catalyst, afforded two crystalline chiral compounds. Through X-ray diffraction analysis, these products were identified as a double acetonide derived from the (E)-oxime and a cyclic nitrone derived from the (Z)-oxime. The additions of organolithium and organomagnesium reagents to the C=N bond of the nitrone were found to be diastereoselective. The addition products are useful intermediates for the preparation of α,α- disubstituted α-aminoacids and other nitrogen-containing compounds in enantiopure form.
View MoreWuhan Benjamin Pharmaceutical Chemical Co.,Ltd
Contact:86-27-52341789
Address:Room 1518 B suite, optical valley time square, No 111 Guanshan Road, Hongshan District,Wuhan,Hubei Province,China.
Contact:+86-0512-88957371
Address:shanghai
Shandong Jusage Technology Co.,Ltd.
Contact:86-13406130167
Address:No.20,North Ride No.9 Road, Guangrao Economic Development Zone, Shandong Province
Wuhan Yitongtai Science and Technology Co.,Ltd.
Contact:+86-27-88933550
Address:27th Fl. Bldg. 1, Shuian International Mansion, Heping Ave, Wuhan, Hubei, China
Yuan Shi(SuQian)Biotechnology Co.,Ltd
website:http://www.yuanshibio.com
Contact:+86-527-84226672
Address:jiangsu suqian
Doi:10.1016/j.bmcl.2004.07.023
(2004)Doi:10.1016/0040-4020(82)80104-X
(1982)Doi:10.1021/jo9722414
(1998)Doi:10.1016/s0020-1693(97)06020-9
(1998)Doi:10.1016/S0277-5387(97)00277-5
(1998)Doi:10.1016/0022-328X(88)80541-2
(1988)