Novel diastereomeric thymidine cyclic 3',5'-threo-phosphoramidates

Article abstract of DOI:10.1080/07328319808004235

Novel diastereomeric thymidine cyclic 3',5'-threo-phosphoramidates were prepared by the treatment of 5'-azido derivative of threo-thymidine with triphenyl phosphite as well as by the treatment of the corresponding amino derivative with phenyl phosphodichloridate. Phosphoramidation of the regioisomeric 3'- and 5'-azido derivatives of erythro-thymidine by means of triphenyl phosphite afforded the open-chain 3'- and 5'-phosphoramidates. The reaction which afforded the cyclic products was assumed to proceed via the cyclic tetraoxazaphosphorane intermediates.

Full text of DOI:10.1080/07328319808004235

Nucleosides and Nucleotides
ISSN: 0732-8311 (Print) (Online) Journal homepage: http://www.tandfonline.com/loi/lncn19
Novel Diastereomeric Thymidine Cyclic 3′,5′-threo-
Phosphoramidates
Darinka Katalenić & Mladen Žinić
To cite this article: Darinka Katalenić & Mladen Žinić (1998) Novel Diastereomeric Thymidine
Cyclic 3′,5′-threo- Phosphoramidates, Nucleosides and Nucleotides, 17:7, 1231-1236, DOI:
10.1080/07328319808004235
To link to this article: http://dx.doi.org/10.1080/07328319808004235
Published online: 21 Aug 2006.
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Date: 12 June 2016, At: 09:57