Synthesis of a non-peptide analogue of omega-conotoxin MVIIA

DOI: 10.1016/S0040-4039(98)01657-8

Source and publish data:

Tetrahedron Letters p. 7619 - 7622 (1998)

Update date:2022-09-26

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Authors:

Menzler, Stefan

Bikker, Jack A.

Horwell, David C.

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Article abstract of DOI:10.1016/S0040-4039(98)01657-8

An efficient synthesis of an alkylphenyl ether based peptidomimetic is described. The compound mimics three key amino acids of omega-conotoxin MVIIA from the cone shell Conus magus and may provide an entry to the design of low molecular weight antagonists of N-type neuronal calcium channels.

Full text of DOI:10.1016/S0040-4039(98)01657-8

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