Intramolecular synthesis of N thiophosphonylated thiopeptides. The case of thiosarcosine

DOI: 10.1016/S0040-4039(98)01982-0

Source and publish data:

Tetrahedron Letters p. 8841 - 8844 (1998)

Update date:2022-09-26

Topics:

Authors:

Alibert, Sonia

Crestia, Dominique

Dujols, Frederic

Mulliez, Michel

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(98)01982-0

A new, three-step, method is proposed for the synthesis of thiopeptides. Each step is verified starting from a sarcosylthiophosphondiamide model and using alcohols or water for the last one. With amines a different regioselective attack on the thiocarbonyl, instead of on the thiophosphoryl with alcohols, is observed.

Full text of DOI:10.1016/S0040-4039(98)01982-0

Products guided by the article

Product name:Benzyl-[1,2,3-trimethyl-2-thioxo-2λ⁵-[1,3,2]diazaphospholidin-(4Z)-ylidene]-amine

Cas No:218954-61-1

R&D Labs maybe for 218954-61-1

Shanghai Hohance Chemical Co., ltd

Contact:13914753421

Address:Fl.5；Bld. 70, Lane 1500; Xinfei Road
Huayi Isotopes Co.

Contact:+ 86 512 52491118

Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
Shanghai Rainbow Chemistry Co., Ltd.

Contact:+86-21-64968086-5815/5812

Address:3rd floor, Building 7, 251 Faladi Road, Zhangjiang Hi-Tech Park, Pudong District, Shanghai, P.R. China
Jiangsu Feymer Technology Co., Ltd.

Contact:+86-512-58110132

Address:Fenghuang Town, Zhangjiagang City, Jiangsu Province, China
Tianjin Anda North Industrial & Business Co.Ltd.

Contact:86-22-24999306

Address:No.11 Erwei Road,Dongli Development Area,Tianjin,China

Relevant to this article

Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (5-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants

Doi:10.1021/jm801330n
(2009)
Synthesis of proline-modified analogues of the neuroprotective agent glycyl-L-prolyl-glutamic acid (GPE)

Doi:10.1016/j.tet.2005.08.026
(2005)
A chiron approach to the cyclopropyl lactone oxylipins

Doi:10.1016/S0957-4166(98)00413-3
(1998)
Bespoke photoreductants: Tungsten arylisocyanides

Doi:10.1021/ja510973h
(2015)
Biosynthesis of the lincomycins. 1. Studies using stable isotopes on the biosynthesis of the propyl- anbd ethyl-L-hygric acid moieties of lincomycins A and B

Doi:10.1021/ja00337a038
(1984)
Imide and lactam derivatives of N-benzylpyroglutamyl-L-phenylalanine as VCAM/VLA-4 antagonists

Doi:10.1016/S0960-894X(00)00582-5
(2001)

Article Doi