Tetrahedron Letters p. 8841 - 8844 (1998)
Update date:2022-09-26
Topics:
Alibert, Sonia
Crestia, Dominique
Dujols, Frederic
Mulliez, Michel
A new, three-step, method is proposed for the synthesis of thiopeptides. Each step is verified starting from a sarcosylthiophosphondiamide model and using alcohols or water for the last one. With amines a different regioselective attack on the thiocarbonyl, instead of on the thiophosphoryl with alcohols, is observed.
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