A new type of nucleotide analogue with 4-pyridylphosphonate internucleotide linkage

DOI: 10.1016/S0040-4039(99)00702-9

Source and publish data:

Tetrahedron Letters p. 4263 - 4266 (1999)

Update date:2022-08-02

Topics:

Authors:

Kers, Annika

Stawinski, Jacek

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Article abstract of DOI:10.1016/S0040-4039(99)00702-9

Suitably protected dithymidine H-phosphonates were quantitatively converted into the corresponding dinucleoside 4-pyridylphosphonates by treatment with 1,8-diazabicylo[5.4.0]undec-7-ene (DBU) in the presence of trityl chloride in pyridine. The reaction wa

Full text of DOI:10.1016/S0040-4039(99)00702-9

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