Archiv der Pharmazie p. 50 - 54 (1999)
Update date:2022-07-30
Topics:
Daidone, Giuseppe
Raffa, Demetrio
Maggio, Benedetta
Plescia, Fabiana
Cutuli, Vincenza Maria Catena
Mangano, Nunzio Guido
Caruso, Antonina
Several new 3-(Isoxazol-3-yl)-quinazolin-4(3H)-one derivatives were synthesized and tested for their analgesic and antiinflammatory activities, as well as for their acute toxicity and ulcerogenic effect. A few compounds were as active as phenylbutazone in the writhing and acetic acid peritonitis tests. They had a very low ulcerogenic effect.
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(2008)
