Tetrahedron Letters p. 5987 - 5988 (1999)
Update date:2022-08-03
Topics:
Wessig, Pablo
A novel synthetic route to bicyclic β-turn dipeptides (BTD) is described. It starts with L-β-benzoylalanine 1, which is N-protected and coupled with proline esters yielding the dipeptides 3. Upon irradiation 3a-c undergo a cyclization to the indolizinones 4 in a highly stereoselective manner. 4a and 4c were converted into the N-protected BTD derivatives suited for peptide synthesis. The absolute configuration of products 4 and 5 were unambiguously elucidated from NOE results.
View MoreShanDong XinDa Chemical CO.,LTD
Contact:086-0311-87580543
Address:No.168, High Technology Development Zone Jinan Shandong China
Changyi Xinxing Technology Development Co., Ltd.
Contact:0086-510-86651065(Time Zone:8),86651656
Address:94 Yingbinxilu WestRoad, Huangtu Town, Jiangyin City, Jiangsu, China
Contact:+44 7958 511245
Address:PO Box 469, Manchester, UK
SHENYANG COMEBOARD TECHNOLOGY CO., LTD
Contact:+86-24-25724626
Address:Room2210,Tianbao International Building,No.8-1 Weigong South Street,Tiexi District,Shenyang,China
Contact:+86-574- 87178138; 87297407
Address:No. 809, Liudingxingzuo, cangsong road, Ningbo, China
Doi:10.1021/jo990811p
(1999)Doi:10.1021/jo00833a030
(1970)Doi:10.1016/S0040-4039(01)88689-5
(1969)Doi:10.1016/S0022-328X(99)00210-7
(1999)Doi:10.1021/jo990639p
(1999)Doi:10.1055/s-2007-983850
(2007)