Asymmetric total synthesis of (-)-prosophylline

DOI: 10.1016/S0040-4039(99)01387-8

Source and publish data:

Tetrahedron Letters p. 6869 - 6870 (1999)

Update date:2022-08-03

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Authors:

Koulocheri, Sofia D.

Haroutounian, Serkos A.

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Article abstract of DOI:10.1016/S0040-4039(99)01387-8

The asymmetric total synthesis of (-)-prosophylline from D-glucal via (2S)-hydroxymethyl-dihydropyridone 6 by a 17-step synthesis and 12% overall yield is presented.

Full text of DOI:10.1016/S0040-4039(99)01387-8

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