Regioselective synthesis of chiral six- and seven-membered N- heterocycles from N-allyl carbohydrate nitrones: Tuning of regioselectivity by N-substitution

Article abstract of DOI:10.1016/S0040-4020(99)00694-8

The intramolecular cycloaddifion of N-allyl carbohydrate nitrones leads to enantiomerically pure six- and seven-membered nitrogen heterocycles and the regio-selectivity of the cycloaddition was controlled by changing the substituent on the nitrogen atom of the N-allyl moiety.