Enzymatic resolution of (±)-2-(N(β)-t-butoxycarbonyl-N(α)- methylhydrazino)cycloalkanols

DOI: 10.1016/S0957-4166(99)00535-2

Source and publish data:

Tetrahedron Asymmetry p. 4619 - 4626 (1999)

Update date:2022-08-04

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Authors:

Forro, Eniko

Szakonyi, Zsolt

Fueloep, Ferenc

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Article abstract of DOI:10.1016/S0957-4166(99)00535-2

Racemates of cis- and trans-2-(N(β)-t-butoxycarbonyl-N(α)- methylhydrazino)cyclopentanols and -cyclohexanols 1-4 were resolved through lipase PS- or Novozym 435-catalysed asymmetric acylation of the secondary OH group at the (R)-stereogenic centre. High e

Full text of DOI:10.1016/S0957-4166(99)00535-2

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