Chemical and Pharmaceutical Bulletin p. 81 - 84 (2000)
Update date:2022-07-31
Topics:
Murase, Masayuki
Watanabe, Kazuhiro
Yoshida, Takuji
Tobinaga, Seisho
The nucleophilic addition reaction of N-tosyl-4-oxo-4,5,6,7- tetrahydroindole (12) with the lithium salt of 1-methoxyindole (5), followed by dehydration with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) gave the derivative of 2,4'-bi-1H-indole (9) which provides a new concise synthetic method of an indole pigment of the slime mould, arcyriacyanin A. The compound was first demonstrated here to have unique inhibitory activity to a panel of human cancer cell lines and to inhibit protein kinase C and protein tyrosine kinase.
View MoreJinan Trio PharmaTech Co., Ltd
Contact:86-531-88811783；+(0)13153010282
Address:2766 Yingxiu Road, Jinan High-Tech Zone, China
Shanghai agrotree chemical co.,ltd.
Contact:+86-21-50117563
Address:Room 8A,liangfeng building,No.8 dongfang RD.pudong,shanghai,China
Anhui Gusheng Import&Export CO.,LTD
Contact:86-551-63662296
Address:Jinzhai Road NO.162 ,hefei, china
website:https://www.bocsci.com/
Contact:1-631-485-4226
Address:Ramsey Road
Hubei ShiNan Pharmaceutical Chemical co., Ltd.(expird)
Contact:+86-13554447107
Address:Wuhan HongShanOu wu no road 378 future residence building 1 unit 14 layer no. 1401 A
Doi:10.1021/jm00296a017
(1970)Doi:10.1021/np9904004
(2000)Doi:10.1016/S0040-4020(01)82723-X
(1969)Doi:10.1021/ol802609j
(2009)Doi:10.1039/J19700000944
()Doi:10.1246/cl.2000.122
(2000)
