Efficient recycling of a chiral palladium catalytic system for asymmetric allylic substitutions in ionic liquid

Article abstract of DOI:10.1039/c1cc12157j

Chiral carbohydrate-based diphosphites were used for Pd-catalysed asymmetric allylic substitution (alkylation, amination, phosphination) in neat ionic liquids (ILs). Pyrrolidinium-based IL led to the best activities, allowing an efficient catalyst immobilization. In the allylic amination (TOF > 3100 h^-1), the catalyst could be recycled nine times preserving both activity and enantioselectivity.