Enantioselective Synthesis of γ-Hydroxynorvaline

DOI: 10.1055/s-1997-3246

Source and publish data:

Synlett p. 691 - 692 (1997)

Update date:2022-08-03

Topics:

Authors:

Jacob Jacob

Roumestant

Viallefont

Martinez

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Article abstract of DOI:10.1055/s-1997-3246

A new synthesis of enantiomerically pure γ-hydroxynorvaline is described. The key step involves diastereoselective alkylation of the chiral Schiff base 1 with primary iodo derivatives 2 easily prepared from propylene oxide.

Full text of DOI:10.1055/s-1997-3246

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