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Acknowledgements
The Mexican National Council for Science and
Technology (CONACYT),The Mexican Ministry of
Public Education (SEP), The Ministry of Higher
Education of Malaysia (MOHE) andThe RoyalThai
Government are acknowledged for the support to
the authors of this work. The UK Engineering and
Physical Sciences Research Council (EPSRC) is
thanked for the support of the multidisciplinary Bio-
catalysis Integrated with Chemistry and Engineering
(BiCE) programme (GR/S62505/01) at University
College London (London, UK). The help from the
thirteen industrial partners supporting the BiCE
programme is also acknowledged.
Hussain HA, Ward JM. (2003) Enhanced Heterologous Expres-
sion of Two Streptomyces griseolus Cytochrome P450s and
Streptomyces coelicolor Ferredoxin Reductase as Potentially
Efficient Hydroxylation Catalysts. Appl Environ Microbiol 69:
373–382.
Ingram CU, Bommer M, Smith MEB, Dalby PA, Ward J. M.,
Hailes HC, Lye GJ. 2007. One-pot synthesis of amino-alcohols
using a de-novo transketolase and β-alanine:pyruvate transami-
nase pathway in Escherichiacoli. Biotechnol Bioeng 96:
559–569.
Islam RS, Tisi D, Levy MS, Lye GJ. (2008) Scale-up of E. coli
growth and recombinant protein expression conditions from
microwell to laboratory and pilot scale based on matched kLa.
Biothecnol Bioeng 99:1128–1139.
Kaldor WK, Kalish VJ, Davies JF, Shetty BV, Fritz JE, Appelt K,
et al. 1997. Viracept (Nefinavir Mesylate, AG1343): A potent,
orally available inhibitor of HIV-1 protease. J Med Chem 40:
3979–3985.
Kaulmann U, Smithies K, Smith MEB, Hailes HC, Ward JM.
2007. Substrate spectrum of ω-transaminase from Chromobac-
terium violaceum DSM30191 and its potential for biocatalysis.
Enz Microb Tech 41:628–637.
Declaration of interest: The authors report no
conflicts of interest. The authors alone are respon-
sible for the content and writing of the paper. The
studentships was supported by the Mexican National
Council for Science and Technology (CONACYT),
the Mexican Ministry of Public Education (SEP),
the Ministry of Higher Education of Malaysia
(MOHE) and he Royal Thai Government.More-
over, financial support was provided bythirteen
industrial partners supporting the BiCE pro-
gramme.
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