Bioorganic and Medicinal Chemistry Letters p. 3323 - 3329 (2006)
Update date:2022-08-04
Topics:
Shimizu, Kazuki
Kawase, Akira
Haneishi, Tsuyoshi
Kato, Yasuharu
Kinoshita, Kazutomo
Ohmori, Masayuki
Furuta, Yoshiyuki
Emura, Takashi
Kato, Nobuaki
Mitsui, Tetsuya
Yamaguchi, Koji
Morita, Keiichi
Sekiguchi, Nobuo
Yamamoto, Tessai
Matsushita, Tomochika
Shimaoka, Shin
Sugita, Atsuko
Morikawa, Kazumi
Design, synthesis, and in vitro and in vivo evaluation of a series of antipsoriatic antedrugs having 16-en-22-oxa-vitamin D3 are described. Among the seven compounds examined, two are promising: ester 5c and amide 5f, both of which exhibit grea
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