ACS Medicinal Chemistry Letters p. 758 - 763 (2011)
Update date:2022-08-05
Topics:
Duffy, John P.
Harrington, Edmund M.
Salituro, Francesco G.
Cochran, John E.
Green, Jeremy
Gao, Huai
Bemis, Guy W.
Evindar, Ghotas
Galullo, Vincent P.
Ford, Pamella J.
Germann, Ursula A.
Wilson, Keith P.
Bellon, Steven F.
Chen, Guanging
Taslimi, Paul
Jones, Peter
Huang, Cassey
Pazhanisamy
Wang, Yow-Ming
Murcko, Mark A.
Su, Michael S.S.
The synthesis of novel, selective, orally active 2,5-disubstituted 6H-pyrimido[1,6-b]pyridazin-6-one p38α inhibitors is described. Application of structural information from enzyme-ligand complexes guided the selection of screening compounds, leading to t
View MoreContact:+1-284-4950244
Address:Box 3069, Road Town, Tortola, British Virgin Islands
Shenzhen Feiming Science and Technology Co,. Ltd
Contact:+86-755-85232577
Address:#B2309, Fenglin International Center ,Jixiang Road, Longcheng street, LongGang District, Shenzhen city, Guangdong province, China.
Contact:+86-021-58123769
Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
Anyang Double Circle Auxiliary CO.,LTD
Contact:0086-134 6082 4403
Address:dongfeng road, anyang city, henan province,china
Contact:+36(21)2523420
Address:Head office: 1102 Budapest, SZENT LASZLO TER 24/B. 1/1., HUNGARY / CHINA
Doi:10.1016/S0277-5387(00)00616-1
(2001)Doi:10.1128/AAC.46.12.3869-3876.2002
(2002)Doi:10.1016/S0040-4020(02)01122-5
(2002)Doi:10.1021/ma051536d
(2005)Doi:10.1021/ja00749a034
(1971)Doi:10.1055/s-2001-11449
(2001)
