
Tetrahedron Letters p. 1315 - 1318 (1995)
Update date:2022-08-05
Topics:
Suau, Rafael
Valpuesta, Maria
Torres, Gregorio
A new approach to the synthesis of 7,8-dioxygenated tetrahydroisoquinoline alkaloids based on the photo-Fries rearrangement of esters derived from 3-hydroxy-4-methoxy phenylacetonitrile is reported. The procedure was applied to the synthesis of the alkaloid Arizonine and 1-benzyl tetrahydroisoquinoline precursor of cularine and 1,2-berbine alkaloids.
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