Bioorganic and Medicinal Chemistry Letters p. 775 - 778 (1997)
Update date:2022-08-05
Topics:
Empfield
Mayhugh
Ohnmacht
Frank
Grant
Li
Sulfonamides are viable replacements for the phenylsulfonyl and benzoyl moieties initially described for the anilide tertiary carbinol series of K(ATP) potassium channel openers. The SAR of this new series and the synthetic chemistry employed to generate its members are described.
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Doi:10.1021/jo01283a029
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