Synthesis of higher-carbon sugars by addition of organometallic reagents to aldehydes or lactols derived from carbohydrates

Article abstract of DOI:10.1016/S0040-4020(01)00410-0

The addition of different Grignard or lithium organometallic reagents to lactols (1, 6, 21) or aldehydes (10), derived from D-glucose or D-mannose, to give the new higher-carbon sugars (2, 3, 7-9, 13-19, 22 and 23) is reported.