Synthesis of new 2-{[(phenoxy or phenyl)acetyl]amino}benzoic acid derivatives as 3α-hydroxysteroid dehydrogenase inhibitors and potential antiinflammatory agents

Article abstract of DOI:10.1002/ardp.19953281004

A number of 2-{[(phenoxy or phenyl)acetyl]amino}benzoic acid derivatives were prepared in about 50% yield from (phenoxy or phenyl)acetyl chloride and anthranilic acid derivatives. All the compounds were tested as in vitro inhibitors of 3α-hydroxysteroid d