1-Phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes and Related Derivatives as Ligands for the Neuromodulatory ?3 Receptors: Further Structure-Activity Relationships

DOI: 10.1021/jm00019a016

Source and publish data:

Journal of Medicinal Chemistry p. 3857 - 3864 (1995)

Update date:2022-08-04

Topics:

Authors:

Wyrick, Steven D.

Booth, Raymond G.

Myers, Andrew M.

Owens, Constance E.

Bucholtz, Ehren C.

et al. et al.

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Article abstract of DOI:10.1021/jm00019a016

A series of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes (1-phenyl-3-aminotetralins, PATs) previously was found to stimulate tyrosine hydroxylase activity and dopamine synthesis in rat brain through interaction with a novel ?₃ receptor.Speci

Full text of DOI:10.1021/jm00019a016

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