Organosulfur compounds as potential fungicides: The preparation and properties of some substituted benzyl 2-hydroxyethyl oligosulfides

Article abstract of DOI:10.1080/10426500008043656

Compounds of the general type ArCH₂S_nCH₂CH₂OH (n = 1 - 4, Ar = Ph, 2-MeC₆H₄. 4-MeC₆H₄, 4-ClC₆H₄, 4-MeOC₆H₄; n = 1 - 3, Ar = 2-ClC₆H₄; n = 2, Ar = 4-FC₆H₄; n = 3 or 4, Ar = 2-furyl) have been prepared as analogues of the trisulfide PhCH₂SSSCH₂CH₂OH (an antimicrobial compound which occurs in the plant Petiveria alliacea) and their potential for application as agricultural fungicides has been examined. In vitro tests against Fusarium culmorum, Fusarium oxysporum and Gauennmyceles graminis showed that all compounds gave > 80% control of these organisms at 1000 ppm. Tests at 100 and 10 ppm showed varying levels of control but the activity did not depend significantly on the number of sulfur atoms present. Selected compounds were also shown to be active in vivo against Erysiphe graminis on barley seedlings, Botrytis fabae and Uromyces viciae-fabae on bean seedlings, Podosphaera leucotricha on apple seedlings, and Phytophthora infestans on potato leaf. The compounds were phytotoxic at concentrations greater than 0.33%.

Full text of DOI:10.1080/10426500008043656

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Phosphorus, Sulfur, and Silicon
and the Related Elements
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ORGANOSULFUR COMPOUNDS
AS POTENTIAL FUNGICIDES:
THE PREPARATION AND
PROPERTIES OF SOME
SUBSTITUTED BENZYL
2-HYDROXYETHYL
OLIGOSULFIDES
Ezekiel T. Ayodele a , Harry R. Hudson a , Isaac A.O.
Ojo a b & Max Pianka a
a School of Applied Chemistry, University of North
London , Holloway Road, London, N7 8DB, United
Kingdom
b Obafemi Awolowo University , Ile-lfe, Nigeria
Published online: 04 Oct 2006.
To cite this article: Ezekiel T. Ayodele , Harry R. Hudson , Isaac A.O. Ojo & Max
Pianka (2000) ORGANOSULFUR COMPOUNDS AS POTENTIAL FUNGICIDES: THE
PREPARATION AND PROPERTIES OF SOME SUBSTITUTED BENZYL 2-HYDROXYETHYL
OLIGOSULFIDES, Phosphorus, Sulfur, and Silicon and the Related Elements, 159:1,
123-142, DOI: 10.1080/10426500008043656
To link to this article: http://dx.doi.org/10.1080/10426500008043656
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