Bioscience, Biotechnology and Biochemistry p. 1146 - 1151 (1996)
Update date:2022-09-26
Topics:
Aono, Rikizo
Doukyu, Noriyuki
Pseudomonas sp. strain ST-200 isolated from a humus soil effectively oxidizes cholesterol dissolved in organic solvents but not that suspended in the growth medium. The organism does not assimilate cholesterol. This organism oxidized a variety of 5α- or 5-ene-steroids dissolved in organic solvent. First, the 3β-OH group was oxidized to a ketone group. The 3α-OH group was scarcely oxidized. Successively, C-6 position of 5-ene-steroids was hydroxylated, and a double bond of 5-ene-steroids was transferred from Δ5 to Δ4. Then, the 6-OH group was oxidized to a ketone group. Persolvent fermentation with ST-200 would provide an effective, convenient, and stereospecific method to oxidize the C-3 and C-6 positions of steroids.
View Morewebsite:http://www.sjc.com.tw
Contact:(886) 2-2396-6223
Address:14Fl., No. 99. Sec. 2, Jen Ai Road
Shanghai Bosman Industrial Co., Ltd
Contact:86-21-63065878-8006
Address:Rm907, No.1611, North Sichuan Road, Hongkou District, Shanghai, 200080 China
Valiant Fine Chemicals Co., Ltd.
Contact:+86 535 6101878/6374484
Address:11 Wuzhishan Rd.,YTETDZ,Yantai,264006,Shandong,China
Jewim Pharmaceutical (Shandong) Co., Ltd
Contact:+8615621883869
Address:山东省泰安市高新技术产业开发区配天门大街西首
Contact:+86-518-81061113
Address:No. 8 Lingzhou Road, Lianyungang, Jiangsu, China
Doi:10.1021/ja029963j
(2003)Doi:10.1016/S0040-4020(99)00628-6
(1999)Doi:10.1002/jps.2600630145
(1974)Doi:10.1016/j.tetlet.2010.06.119
(2010)Doi:10.1021/jm00333a020
(1964)Doi:10.1002/hc.10139
(2003)
