A new and unusually flexible route to cyclopentanoids synthesis of sarkomycin and prostaglandins

Article abstract of DOI:10.1016/S0040-4039(00)99968-4

Combination of the dianion of dialky 3-hexenedioate and β-bromopropionate leads directly to a 2,3-disubstituted cyclopentanone, which can be transformed to a variety of primary prostaglandins and sarkomycin.