A practical one-pot process for α-amino aryl ketone synthesis

DOI: 10.1016/j.tetlet.2005.09.183

Source and publish data:

Tetrahedron Letters p. 8587 - 8589 (2005)

Update date:2022-09-26

Topics: Monitor the reaction Workup and Purification Stir and Heat

Authors:

Conrad, Karen

Hsiao, Yi

Miller, Ross

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Article abstract of DOI:10.1016/j.tetlet.2005.09.183

An efficient, convenient, high-yielding synthesis of α-amino aryl ketones is described, involving the one-pot deprotonation-transmetallation- arylation of a Weinreb amide while retaining chirality of the original amide.

Full text of DOI:10.1016/j.tetlet.2005.09.183

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