SYNTHESIS OF 2,4-DI(p-FORMYL)- alpha -TRUXILLIC ACID BY CRYSTAL ENGINEERING.

Article abstract of DOI:10.1246/bcsj.57.3335

p-Formylcinnamic acid, which usually crystallizes in either the beta -form or gamma -form of packing, was converted into its diethyl acetal. The introduction of such bulky groups onto a benzene ring successfully provided the authors with the alpha -form of packing, from which the desired photodimer, 2,4-di(p-formyl)- alpha -truxillic acid (c-2, t-4-bis(p-formylphenyl)-5-1, t-3-cyclobutanedicarboxylic acid) was obtained with a yield of 85-90%.