
Bioorganic and Medicinal Chemistry Letters p. 1035 - 1040 (1998)
Update date:2022-08-04
Topics:
Scherkenbreck, Juergen
Harder, Achim
Plant, Andrew
Dyker, Hubert
The first structure-activity relationships of the anthelmintic cyclooctadepsipeptide PF1022A have been established via a systematic exchange of the leucine residues by a series of related N-alkylated amino acids. The data presented strongly suggest that (
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