PF1022A - A novel anthelmintic cyclooctadepsipeptide. Modification and exchange of the N-methyl leucine residues

DOI: 10.1016/S0960-894X(98)00156-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1035 - 1040 (1998)

Update date:2022-08-04

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Authors:

Scherkenbreck, Juergen

Harder, Achim

Plant, Andrew

Dyker, Hubert

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Article abstract of DOI:10.1016/S0960-894X(98)00156-5

The first structure-activity relationships of the anthelmintic cyclooctadepsipeptide PF1022A have been established via a systematic exchange of the leucine residues by a series of related N-alkylated amino acids. The data presented strongly suggest that (

Full text of DOI:10.1016/S0960-894X(98)00156-5

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Product name:L-Leucine, N-methyl-N-(phenylmethyl)-

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