Methyltrioxorhenium catalysed synthesis of highly oxidised aryltetralin lignans with anti-topoisomerase II and apoptogenic activities

DOI: 10.1016/j.bmc.2005.07.017

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Bioorganic and Medicinal Chemistry p. 5949 - 5960 (2005)

Update date:2022-09-26

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Authors:

Saladino, Raffaele

Fiani, Cinzia

Belfiore, Maria Cristina

Gualandi, Giampiero

Penna, Sabrina

Mosesso, Pasquale

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Article abstract of DOI:10.1016/j.bmc.2005.07.017

A novel and efficient procedure to prepare highly oxidised aryltetralin lignans, such as isopodophyllotoxone and (-)-aristologone derivatives, by oxidation of podophyllotoxin and galbulin with methylrhenium trioxide (MTO) and novel MTO heterogeneous catal

Full text of DOI:10.1016/j.bmc.2005.07.017

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