6,7-Dihydroxy-3-chromanamine: Synthesis and Pharmacological Activity of an Oxygen Isostere of the Dopamine Agonist 6,7-Dihydroxy-2-aminotetralin

DOI: 10.1021/jm00376a020

Source and publish data:

Journal of Medicinal Chemistry p. 1340 - 1343 (1984)

Update date:2022-08-05

Topics:

Authors:

Horn, A. S.

Kaptein, B.

Mulder, T. B. A.

Vries, J. B. de

Wynberg, H.

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Article abstract of DOI:10.1021/jm00376a020

6,7-Dihydroxy-3-chromanamine, the oxygen isostere of 6,7-dihydroxy-2-aminotetralin (6,7-ADTN), has been synthesized and its dopaminergic activity in various test systems determined. Following bilateral injection into the rat nucleus accumbens, a pattern o

Full text of DOI:10.1021/jm00376a020

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