6,7-Dihydroxy-3-chromanamine: Synthesis and Pharmacological Activity of an Oxygen Isostere of the Dopamine Agonist 6,7-Dihydroxy-2-aminotetralin

DOI: 10.1021/jm00376a020

Source and publish data:

Journal of Medicinal Chemistry p. 1340 - 1343 (1984)

Update date:2022-08-05

Topics:

Authors:

Horn, A. S.

Kaptein, B.

Mulder, T. B. A.

Vries, J. B. de

Wynberg, H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00376a020

6,7-Dihydroxy-3-chromanamine, the oxygen isostere of 6,7-dihydroxy-2-aminotetralin (6,7-ADTN), has been synthesized and its dopaminergic activity in various test systems determined. Following bilateral injection into the rat nucleus accumbens, a pattern o

Full text of DOI:10.1021/jm00376a020

Products guided by the article

Product name:4H-1-Benzopyran-4-one, 2,3-dihydro-6,7-dimethoxy-, O-[(4-methylphenyl)sulfonyl]oxime

Cas No:64173-08-6

R&D Labs maybe for 64173-08-6

Guangzhou Probig Fine Chemical Co., Ltd.

Contact:020-86297874

Address:No.2, 1/F, No.20, Hetai Road,Hebian Village, Baiyun District,Guangzhou,China
Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

website:http://www.jlpharms.com

Contact:86-571-86982636

Address:Rm A606, Fuyi Center, jianqiao street
Tosta Enterprise Co., Ltd.

Contact:+86-134-5286-9121

Address:Add: Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong,
Changsha Yonta Industry Co., Ltd.

Contact:+ 86-731-8535 2228

Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
Xi'an Kaixiang Photoelectric Technology Co., Ltd

website:http://www.kxmaterials.com/

Contact:86-29-15991651477

Address:Building 6, Biopharmaceutical Industry R&D Cluster Base, No. 16, Caotang 4th Road, Caotang Science and Technology Industrial Base, High-tech Zone, Xi'an City, Shaanxi Province, China

Relevant to this article

One-pot synthesis of 4-methylisoquinolines via a sequential Pd-catalyzed Heck reaction and intramolecular cyclization

Doi:10.1039/c3ob41680a
(2013)
Doi:10.1002/hlca.19660490313
(1966)
Carbon-bridged tri(cyclopentadiene): Synthesis and coordination with ytterbium

Doi:10.1002/cjoc.201400598
(2014)
Practical Synthesis of 1,2,3,4-Tetrahydroisoquinoline-1-phosphonic and -1-phosphinic Acids through Kabachnik-Fields and Aza-Pudovik Reaction

Doi:10.1055/s-0039-1690755
(2020)
Enantiomerically pure N-aryl-β-amino alcohols by enzymatic resolution

Doi:10.1016/S0957-4166(99)00401-2
(1999)
One-pot synthesis of precocene I and II and a formal synthesis of robustadial A and B via 2-phenyl-4H-1,3,2-benzodioxaborin

Doi:10.1139/v94-237
(1994)

Article Doi