A convenient one-pot synthesis of 4-amino-3-arylpyrazoles from α- phthaloylaminoacetophenones

DOI: 10.1016/S0040-4039(98)01776-6

Source and publish data:

Tetrahedron Letters p. 8229 - 8232 (1998)

Update date:2022-08-03

Topics:

Authors:

Chen, Chen

Wilcoxen, Keith

McCarthy, James R.

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Article abstract of DOI:10.1016/S0040-4039(98)01776-6

Condensation of α-phthaloylaminoacetophenones 1a-c with N,N- dimethylformamide dimethyl acetal afforded the novel enamines 3a-c. Cyclization of 3 with hydrazine, alkylhydrazine or phenylhydrazine salts (4a- d) gave 4-phthaloylamino-3-arylpyrazoles 7-9 in

Full text of DOI:10.1016/S0040-4039(98)01776-6

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