Facile total synthesis of (±)-α-herbertenol, (±)-α-cuparenone and (±)-HM-1 methyl ether involving alkylation of hindered esters

Article abstract of DOI:10.1016/S0040-4039(99)00835-7

The total syntheses of (±)-α-herbertenol 1, (±)-α-cuparenone 4 and (±)-HM-1 methyl ether 3 have been successfully accomplished involving α,α- dimethylation of the esters 8a, 17 and 8b respectively as key steps.