Synthesis of Diethyl, Di-n-octyl, and Mono- and Dicyclohexano Macrocyclic Polyether-Diester Ligands

Article abstract of DOI:10.1021/jo01306a003

Three series of macrocyclic polyether-diester ligands have been prepared from the reaction of four diethyloligoethylene glycols, 24-27, di-n-octyltetraethylene glycol 28, and mono- and dicyclohexanotetraethylene glycols 29 and 30 with diglycolyl dichloride (products 6-11b), thiadiglycolyl dichloride (products 12-17), and 2,6- pyridinedicarbonyl chloride (products 18-23).Compounds 11 and 17 formed trans-syn-trans and trans-anti-trans isomers, and in the case of compound 11 these isomers were isolated and characterized.The 18-membered-ring compounds 7, 22, and 23 formed solid potassium thiocyanate complexes.