Transition-state analogues as inhibitors for GABA-aminotransferase

DOI: 10.1016/0223-5234(91)90022-F

Source and publish data:

European Journal of Medicinal Chemistry p. 129 - 136 (1991)

Update date:2022-08-02

Topics:

Authors:

Iskander, MN

Andrews, PR

Winkler, DA

Brinkworth, RI

Paola, C Di

et al. et al.

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Article abstract of DOI:10.1016/0223-5234(91)90022-F

Our previous calculations on the reaction catalysed by GABA-aminotransferase (GABA-T) have been utilized in this work in order to synthesize a series of reversible inhibitors of this enzyme.The synthesized transition-state analogues and their precursors i

Full text of DOI:10.1016/0223-5234(91)90022-F

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