10.1002/anie.201800679
Angewandte Chemie International Edition
COMMUNICATION
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intermediate in prebiotic sugar and amino acid synthesis
(Scheme 1).
Experimental Section
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UV/Vis measurements. The matrix temperature was controlled by a
Scientific Instruments 9600-1 Si-diode temperature controller. For
irradiations a mercury high-pressure lamp (HBO 200, Osram) with a
monochromator (Bausch & Lomb) was used (band width ca. 10 nm). IR
spectra were recorded with a Bruker IFS 55 FTIR spectrometer (4500 –
400 cm–1, resolution 0.7 cm–1), while UV/Vis spectra were recorded with
a JASCO V-670 spectrophotometer. For the combination of HVFP with
matrix isolation we employed a homebuilt, water-cooled oven directly
connected to the vacuum shroud of the cryostat. The pyrolysis zone
consisted of an empty quartz tube (inner diameter 8 mm, length of
heating zone 50 mm) resistively heated by a thermocoax wire. The
temperature was controlled by a Ni/CrNi thermocouple. At a distance of
approximately 50 mm, all pyrolysis products were condensed on the
surface of the matrix window at 12 K. In a typical pyrolysis experiment a
gaseous mixture of cyclopropylamine with argon (0.5%) was passed
through the hot pyrolysis tube (1000–1100 °C). The gas flow was
regulated by a Pfeiffer EVN 116 gas dosing valve with separate shut-off.
For all experiments we used Ar of 99.999% purity.
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This work was supported by the Volkswagen Foundation (“What
is Life” grant 92 748). A.K.E. thanks the Fonds der Chemischen
Industrie for a scholarship.
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Keywords: amino acids • matrix isolation • origin of life • prebi-
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