Journal of the Chemical Society. Perkin transactions II p. 1792 - 1799 (1980)
Update date:2022-08-03
Topics:
Ooi, Ngan Sim
Wilson, David A.
Salts of O-(benzimidoyl)benzamidoxime have been obtained by the action of N-chloro- or N-bromo-succinimide, or the halogens, on benzamidoxime.Acetylation of the free base gave the title compound, which underwent a thermal cyclisation, with loss of acetamide, to give 3,5-diphenyl-1,2,4-oxadiazole.The mechanism of the reaction, in diphenyl ether, closely paralleled the thermal cyclisation of O-acetylarylamidoximes and O-aroylacetamidoximes, and is thought to involve a polar cyclisation step followed by rate-determining proton transfer. 13C N.m.r. spectra for 32 oxime, amidoxime, O-acetylamidoxime, 5-methyl-1,2,4-oxadiazol-3-yl, and 3-methyl-1,2,4-oxadiazol-5-yl groups on the phenyl ring are calculated.
View MoreXi'an caijing Opto-Electrical Science & Technology Co., LTD
Contact:+86-29-88294447
Address:NO.168 Zhangba Rd. East, Xi'an, P.R.China
Shanghai Hanhong Scientific Co.,Ltd.
website:http://www.chemvia.com
Contact:+86-21-64541543,54280654,13918533501
Address:Jiachuan Road 245
Contact:+(852) 301-98033
Address:Flat C, 23/F, Lucky Plaza, 315-321 Lockhart Road, Wan Chai, Hong Kong
Contact:+86-18200374913
Address:Hongmei Road, No. 99
Tianjin Tensing Fine Chemical Research Develop Centre
Contact:86-022-23718576,13032267585
Address:2-2-201,13 Guiyuan road,Huayuan Industry district,Tianjin,china
Doi:10.1002/ejoc.202000355
(2020)Doi:10.1039/DT9940002761
(1994)Doi:10.1021/ol500720j
(2014)Doi:10.1007/s11426-013-5024-4
(2014)Doi:10.1016/0040-4039(94)88202-9
(1994)Doi:10.1080/00397919408011331
(1994)
