Diuretic Agents Related to Indapamide. 1. Synthesis and Activity of 1-Substituted 2-(4-Chloro-3-sulfamoylbenzamido)isoindolines

DOI: 10.1021/jm00140a018

Source and publish data:

Journal of Medicinal Chemistry p. 1003 - 1006 (1981)

Update date:2022-08-02

Topics:

Authors:

Cignarella, Giorgio

Sanna, Paolo

Miele, Egidio

Anania, Vittorio

Desole, Maria S.

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Article abstract of DOI:10.1021/jm00140a018

The synthesis of isoindoline analogues of indapamide is described.These substances (4a,c,d) were tested for diuretic activity, and 4a was found to be comparable in potency to indapamide.

Full text of DOI:10.1021/jm00140a018

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