Synthesis of amino carba sugars and conformationally restricted polyhydroxy γ-amino acids from (-)-quinic acid

Article abstract of DOI:10.1002/ejoc.200400282

Efficient syntheses of two novel positional stereoisomers of valiolamine, a potent glycosidase inhibitor, and two polyhydroxy γ-amino acids are reported. The syntheses involve regio- and stereoselective azidolysis of epoxides by trimethylsilyl azide with