
Bulletin of the Chemical Society of Japan p. 1263 - 1264 (1981)
Update date:2022-08-04
Topics:
Torigoe, Keisuke
Motoki, Yoshiaki
Muramatsu, Ichiro
The reaction of N-acylpyroglutamic acid with ammonia proceeds in two pathways.The one results in N-acylglutamine as a product, and the other in pyroglutamic acid and an amide formed from the N-acyl group.The ratio of the yields of the two reactions changes with the N-acyl group, being correlated with the acidity of the carboxylic acid from which the N-acyl group is derived, and also with the steric hindrance of the group.
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Doi:10.1016/j.carres.2004.07.018
(2004)Doi:10.1021/jm0494366
(2004)Doi:10.1246/cl.2004.1554
(2004)Doi:10.1007/BF00905067
(1981)Doi:10.1021/ja00056a069
(1993)Doi:10.1021/ja046124j
(2004)