Journal of Organic Chemistry p. 757 - 761 (1982)
Update date:2022-08-05
Topics:
Saulnier, Mark G.
Gribble, Gordon W.
Treatment of 1-(phenylsulfonyl)-3-iodoindole (6) with 2 equiv of tert-butyllithium (-100 deg C THF) generates essentially quantitatively 3-lithio-1-(phenylsulfonyl)indole (1).Quenching 1 with various electrophiles gives 3-substituted indoles in good yield
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