Monatshefte fur Chemie p. 53 - 58 (1982)
Update date:2022-08-04
Topics: Synthesis Heterocyclic
Elmoghayer, Mohamed Rifaat Hamza
Khalifa, Mohamed Ali Elsayed
Ibraheim, Mohamed Kamal Ahmed
Elnagdi, Mohamed Hilmy
The reaction of ethyl cyanoacetate with α-cyanochalcone (1) leads to the formation of β-enaminoesters (3) via Michael addition.Compound 3 reacts with phenylmagnesium bromide to give the β-enaminoketone 5.Acetylation of 3 gives the acetyl product 4.Each of compounds 1 and 3 reacts with malononitrile to give β-enaminonitrile 6.Phenylhydrazine reacts with 3 to give the hydrazone 7.Similarly 3-phenyl-5-aminopyrazole reacts with 3 to give the Schiff base 8. - Keywords: Enaminopyrans; Michael addition; Pyrans, cleavage of
View MoreALPHA PHARMACEUTICAL CO，LTD JIANGSU
Contact:+86-527-84829968,+86-527-84829998
Address:suqian city
SPRING CHEMICAL INDUSTRY CO.,LTD
Contact:86-187-66672125
Address:linchi industry park.zouping
website:http://www.acrospharmatech.com
Contact:+1-3234804688
Address:Flat/RM 1502,Easey Commercial building 253-261 Hennessy Road,Wanchai，HongKong
Contact:+(852) 301-98033
Address:Flat C, 23/F, Lucky Plaza, 315-321 Lockhart Road, Wan Chai, Hong Kong
Chongqing Rong＆Quan Pharmaceutical Technology Co. , Ltd.
Contact:86-023-65268721
Address:No. 7, Manshanhong Village, Pingdingshan, Shapingba District, Chongqing Province, China
Doi:10.1021/acs.joc.6b01648
(2016)Doi:10.1055/s-1982-29713
(1982)Doi:10.1021/jo00136a005
(1982)Doi:10.1002/ejoc.201801170
(2018)Doi:10.1021/ja00378a052
(1982)Doi:10.1002/hlca.19890720724
(1989)
