A Short Synthesis of the 4-Demethoxy-11-deoxyanthracycline Skeleton. Regiospecific Enolate C-Carboxylation with Carbon Oxysulfide

DOI: 10.1021/jo00137a041

Source and publish data:

Journal of Organic Chemistry p. 3193 - 3195 (1982)

Update date:2022-08-05

Topics:

Authors:

Vedejs, E.

Nader B.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00137a041

Regiospecific C-carboxylation of enolate 2 and COS followed by methylation (CH3I) and cuprous triflate cyclization results in a tetracyclic product 9 which can be converted into 11-deoxyanthracyclines.

Full text of DOI:10.1021/jo00137a041

Products guided by the article

Product name:methyl 2-(methylthiocarbonyl)benzenepropanoate

Cas No:82294-03-9

R&D Labs maybe for 82294-03-9

Skyrun Industrial Co.,Ltd(expird)

website:http://www.chinaskyrun.com

Contact:0086-576-84610586

Address:Chemical Development Zone
Suzhou Lixin Pharmaceutical Co., Ltd.

Contact:86-512-88169812

Address:21 Tangxi Road, Suzhou New District, Suzhou 215151
Shenyang NovPharm Technology Co., Ltd.

Contact:.+86-24-24165786

Address:Room 306, Hongjin Mansion, No. 36-1, Wanliutang Rd., Shenhe District, Shenyang, Liaoning, P.R.C.
Puyang Huicheng Electronic Material Co., Ltd

website:http://huichengchem.weba.testwebsite.cn/index_en.html

Contact:+86-393-8910800

Address:West Section Shengli Road, Puyang457000, China
Henan zhongda Biological Engineering Co., Ltd

Contact:86-28-18109029985

Address:shenzhou road,xuedian industrial estate,zhengzhou city,henan province CHN

Relevant to this article

REDUCTIVE ALKYLATION OF 2-METHOXYBENZOIC ACID DERIVATIVES

Doi:10.1016/S0040-4039(00)87030-6
(1982)
INDANE-1,2,3-TRIONE ; A HIGHLY REACTIVE ENOPHILE

Doi:10.1016/S0040-4039(00)87116-6
(1982)
Stereoselective Reactions of Chiral Enolates. Application to the Synthesis of (+)-Prelog-Djerassi Lactonic Acid

Doi:10.1016/S0040-4039(00)86954-3
(1982)
1,2-Hydrogen migration and alkene formation in the photoexcited states of alkylphenyldiazomethanes

Doi:10.1021/ja00072a014
(1993)
CLUSTER CHEMISTRY. X. PREPARATION OF 1,2-BIS(DIPHENYLPHOSPHINO)ETHANE DERIVATIVES OF Ru3(C0)12: CRYSTAL AND MOLECULAR STRUCTURES OF Ru3(C0)10(μ-Ph2CH2CH2Ph2)

Doi:10.1016/S0022-328X(00)85723-X
(1982)
SYNTHESIS OF THE SULFUR ANALOG OF Δ⁶-PGI₁

Doi:10.1246/cl.1980.1247
(1980)

Article Doi