A Short Synthesis of the 4-Demethoxy-11-deoxyanthracycline Skeleton. Regiospecific Enolate C-Carboxylation with Carbon Oxysulfide

DOI: 10.1021/jo00137a041

Source and publish data:

Journal of Organic Chemistry p. 3193 - 3195 (1982)

Update date:2022-08-05

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Authors:

Vedejs, E.

Nader B.

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Article abstract of DOI:10.1021/jo00137a041

Regiospecific C-carboxylation of enolate 2 and COS followed by methylation (CH3I) and cuprous triflate cyclization results in a tetracyclic product 9 which can be converted into 11-deoxyanthracyclines.

Full text of DOI:10.1021/jo00137a041

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