Journal of the Chemical Society. Perkin transactions II p. 625 - 630 (1982)
Update date:2022-08-04
Topics:
Consiglio, Giovanni
Spinelli, Domenico
Gronowitz, Salo
Hoernfeldt, Anna-Britta
Maltesson, Britta
Noto, Renato
The reactivity of some 5-bromo-2-nitro-3-R-thiophens (Ia-g; R=H, Me, Et, Prn, n-hexyl, Pri, and But), 3,4-dibromo-2-nitro-5-R-thiophens (IIa and b; R=H and Me), 3-bromo-2-nitro-5-R-thiophens (IIIa and b; R=H and Me), and 2-bromo-3-nitro-5-R-thiophens (IVa and b; R=H and Me) with amines and sodium benzenethiolate has been studied in methanol at various temperatures.Piperidinodebromination of compounds (Ia and c) has also been studied in benzene, in dioxan, and in dioxan-water (60:40 and 10:90).Independent of the position of the alkyl group (meta or para with respect to the leaving bromine), an unexpected alkyl activation has been observed, which represents a further exception to the electron-releasing behaviour of alkyl groups.
View MoreSynochem Ingredients Corp., Ltd.
Contact:+86-512-5636 2180
Address:Zhangjiagang Free Trade Zone
Jiangsu Zhenfang Chemical CO.,LTD.(Suzhou Zhenfang Chemical Factory)
Contact:+86-512-69598882
Address:Room1201, Jiayuan Road No.1018, Xiangcheng District, Suzhou, China
SHIFANG SUHONG CHEMICAL CO.,LTD
Contact:+86-838-2224563
Address:Room 1207 Zongchen Sunshine No.128 Taishan South Road,Deyang City,Sichuan China
Zhejiang Golden-Shell Pharmaceutical Co.,Ltd.
Contact:+86-576-87501888 / 87501988
Address:No.89 Zhongxing Road. Li'ao, Yuhuan, Zhejiang, China
Nanjing Chemipioneer Pharma&Tech Co.,Ltd
website:http://www.chemipioneer.com.cn
Contact:+86-25-52685700
Address:Room 305，A Block，Biological-Medicine Building，Business Start-up Center，Xin-ke 1st Road, High-tech development zone，Nanjing city，Jiangsu Province, China
Doi:10.1016/j.bmcl.2004.05.093
(2004)Doi:10.1016/j.bmcl.2003.09.084
(2004)Doi:10.1007/BF00565935
()Doi:10.1021/jm00337a007
(1963)Doi:10.1039/JR9350000818
()Doi:10.1016/S0040-4039(01)99961-7
(1966)
