102
from a primary uterine lesion. Moreover, there was no local
recurrence after the left lung cancer operation so in light of
this and the above-mentioned facts a diagnosis of primary
cardiac leiomyosarcoma was made.
While a recent increase in multiple cancers has been
noticed, cases of double cancer concurrent with primary
leiomyosarcoma of the hart are extremely rare. Patients
with primary cardiac leiomyosarcoma have a poor pro-
gnosis, most of them dying within 1 year after the diagnosis.
The effect of surgical excision and adjuvant therapy for
cardiac leiomyosarcoma should now be evaluated by re-
ference to the many well-described cases in the medical
literature.
Acknowledgment. We are very grateful to Miss Youko Tanaka for her
secretarial assistantance.
Fig. 4. Immunohistochemical examination of the removed tumor mass
was positive for smooth muscle-specific actin (ϫ400)
References
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examination was positive for vimentin, desmin, smooth
muscle-specific actin (Fig. 4), and HHF35, and negative for
S100 protein, factor VIII, and myoglobin. Altogether
the morphological and immunohistochemical findings were
considered consistent with a diagnosis of leiomyosarcoma.
Postoperative recovery was uneventful. However, the
patient died of cerebral infarction on April 2, 1999.
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